静脉内注射中的象限特定疼痛:系统性审查和元分析
Mehmet Cem Sabaner1, Irem Gunes2,3, Abdullah Divarci2
1Department of Ophthalmology, Bilecik Training and Research Hospital, Bilecik, Turkey. drmcemsabaner@yahoo.com.
Ophthalmology and therapy
|March 13, 2026
概括
这项研究发现,静脉内注射 (IVI) 象限之间患者报告的疼痛没有显著差异. 静脉注射的疼痛管理应专注于麻醉和技术,而不是注射部位.
科学领域:
- 眼科医生 眼科 眼科
- 疼痛管理 疼痛管理
- 视网膜疾病 视网膜疾病
背景情况:
- 患者在静脉内注射 (IVI) 期间报告的疼痛可能会影响治疗的坚持.
- 了解按注射象限的疼痛变化对于优化患者舒适至关重要.
研究的目的:
- 为了确定患者报告的疼痛是否在四个主要的静脉内注射象限中有显著差异.
- 为了确定IVI手术中最不痛苦的象限.
主要方法:
- 在13个数据库中进行了系统的文献搜索,根据象限报告IVI疼痛的研究.
- 随机效应的元分析被用来比较所有六个对对象的疼痛分数 (0-10 VAS).
- 七项涉及2048 IVI的研究被纳入了定性审查和元分析.
主要成果:
- 注射象限之间疼痛的综合平均差异很小 (<1VAS单位) 并没有统计学意义,置信区间超过零.
- 在研究中观察到大量异质性 (I2>80%),表明发现不一致.
- 没有一个特定的象限始终表明报告的疼痛减少.
结论:
- 目前的证据不支持一个特定的象限对静脉内注射来说不那么痛苦.
- 显著的异质性限制了关于象限特定疼痛的最终结论.
- 未来的研究应该标准化疼痛评估和象限分配,以调查潜在的微妙差异.
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