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Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
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通过蛋白S和TFPIα-fVshort-protein S复合体抑制血栓的机制

Alexander G Ginsberg1, Josefin Ahnström2, James T B Crawley2

  • 1Department of Mathematics, University of Utah, Salt Lake City, UT, USA.

Biophysical journal
|March 13, 2026
PubMed
概括

蛋白S复合体 (PSC) 通过增强组织因子通路抑制剂α (TFPIα) 来强烈抑制血栓的产生. 数学建模显示,PSC在血小板上的积累会影响出血障碍和血友病A.

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