全球关于败血症内皮糖体的研究趋势:一个图书统计分析
Kamila R Daniyarova1, Zhanslu N Sarkulova1, Amin Tamadon2
1Department of Anesthesiology and Reanimatology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
BioMed research international
|March 13, 2026
概括
对败血症中的内皮葡萄糖 (EG) 的研究显示出显著的增长,其中包括生物标志物和疗法在内的关键主题. 未来的工作应该集中在验证EG生物标志物和开发向治疗.
科学领域:
- 生物医学研究的研究.
- 关键护理医学 关键护理医学
- 血管生物学 血管生物学
背景情况:
- 败血症是一个关键的全球健康问题.
- 内皮葡萄糖 (EG) 功能障碍是败血症发病的核心原因.
- EG降解有助于血管透性,炎症和器官衰竭.
研究的目的:
- 进行全面的图书统计分析全球研究趋势的内皮葡萄糖体 (EG) 在败血症.
- 确定关键的研究主题,有影响力的贡献者和新兴趋势.
- 在毒症的背景下绘制EG研究的演变图.
主要方法:
- 从科学网络和Scopus (2005-2025) 出版物的图书统计分析.
- 包括原始的英语研究文章.
- 使用了Bibliometrix R包来分析出版趋势,引用,协作和关键字的共同出现.
主要成果:
- 从2005年到2023年,研究成果增加了13倍,共计217篇出版物.
- 领先的期刊包括Shock和Critical Care;最大的贡献国是美国,日本和澳大利亚.
- 关键的研究主题包括EG生物标志物,微循环功能障碍和治疗策略,新兴的重点是COVID-19相关的EG损伤和新型成像.
结论:
- 全球关于血症EG的研究经历了指数式增长和重大主题转变.
- 未来的研究应该优先考虑EG生物标志物的验证和有针对性的治疗干预措施的开发.
- 在这个领域提高全球研究公平性也是关键的未来方向.
更多相关视频
05:28Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
4.7K
06:12Modeling the Endothelial Glycocalyx Post-Pneumonectomy in a 3D Fluidic Chip - An Approach to Fabricating a Vascular-based Organ-on-Chip System
Published on: September 16, 2025
766
相关概念视频
Carbohydrate Metabolism
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Diabetes Mellitus: Introduction
Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...
Hyperglycemia
Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
