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Updated: Mar 14, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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使用全基因组测序的沙特肝细胞癌患者的基因组景观:试点研究

Mazen Hassanain1, Yang Liu2, Weam Hussain1

  • 1Department of Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.

Frontiers in gastroenterology (Lausanne, Switzerland)
|March 13, 2026
PubMed
概括

沙特阿拉伯的肝细胞癌 (HCC) 患者表现出与索拉芬尼布耐药性相关的遗传变异. 耐药瘤比敏感瘤有更多的遗传异常,这表明了新的治疗点.

关键词:
在HCC中,HCC是HCC.没有NGS,没有NGS.沙特阿拉伯的沙特阿拉伯人.在WGS中,使用的是WGS.索拉费尼布耐药性 索拉费尼布耐药性

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