青少年双极性障碍中阿戈梅拉丁诱导的主观双重错觉
Yiğit Özaydın1, Birsen Şentürk Pilan2, Tezan Bildik3
1Özaydın, Research Assistant, Ege University, Department of Child and Adolescent Psychiatry, Bornova, İzmir, Türkiye. ORCID: 0009-0006-9441-036X.
Psychopharmacology bulletin
|March 13, 2026
概括
在青少年中使用阿戈梅拉丁可能会引发情绪不稳定和精神病症状,如主观的双重错觉. 停止抗抑郁药和抗精神病治疗导致一个年轻患者的临床状况显著改善.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 妄想错误识别综合征是一种罕见的精神疾病.
- 主观的双重妄想在青少年中特别不常见.
- 抗抑郁药阿戈梅拉丁在儿童群体中证据有限,可能引发情绪不稳定.
研究的目的:
- 报告一个17岁的男性病例,在开始服用阿戈梅拉丁后,他出现了精神病特征的躁狂发作.
- 要强调谨慎使用抗抑郁药在患双相情感障碍风险的青少年中的重要性.
主要方法:
- 一个17岁的男性患有抑郁症状的病例报告.
- 躁狂发作与精神病特征的临床观察,包括主观的双重妄想.
- 停止使用阿戈梅拉丁并开始使用奥兰沙平.
- 使用标准化评分尺度进行症状评估.
主要成果:
- 患者在开始服用阿戈梅拉丁后出现了带有精神病特征的躁狂发作,其特征是主观的双重妄想.
- 在停止服用阿戈梅拉丁并开始服用 olanzapine 后的三周内观察到显著的临床改善.
- 通过标准化评级尺度证实了症状的减少.
结论:
- 在青少年中使用抗抑郁药,特别是那些有双相情感障碍风险的青少年,需要谨慎.
- 密切监测新出现的躁狂或精神病症状至关重要.
- 及时干预是必要的,以防止严重的并发症.
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