在创伤后同时呈现的诺卡迪亚瘤感染和皮肤性性炎症
Igor Dumic1, Ronin Joshua S Cosiquien2, Joshua Jagodzinski1
1Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
Cureus
|March 13, 2026
概括
机械创伤可以触发皮肤炎 (PG) 和无心脏病. 本病例报告详细介绍了一名患有多发性肌痛性风湿症的患者,在受伤后患上了这两种疾病,强调了共同的风险因素和治疗结果.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 皮肤病 (Pyoderma gangrenosum,简称PG) 是一种罕见的中性恋性皮肤病,呈现为痛苦的.
- 皮肤性心脏病可以模仿PG,通常发生在机械创伤后.
- 接受皮质类固醇治疗的老年患者容易患上各种皮肤疾病.
研究的目的:
- 报告一个独特的病例,同时患有皮肤炎和皮肤性心脏病.
- 探索共同的风险因素,包括机械创伤和皮质类固醇使用.
- 讨论这些重叠的疾病的诊断挑战和治疗策略.
主要方法:
- 一个老年患者的病例报告,患有快速进展的皮肤.
- 组织病理学检查和皮肤活检的微生物培养.
- 对皮质类固醇和抗生素治疗反应的临床观察.
主要成果:
- 皮肤活检显示了与PG一致的特征,培养物确定了*Nocardia.
- 患者最初对抗生素没有反应,但用高剂量的皮质类固醇,trimethoprim-sulfamethoxazole和doxycycline恢复过来.
- 实现了完全的临床康复,剩余的炎症后超色素.
结论:
- 机械创伤是PG和皮肤无心病的重要共同风险因素.
- 帕瑟基现象可能有助于受伤后的PG发展.
- *心脏 (Nocardia abscessus) *感染可能会引发PG,需要进一步调查.
相关概念视频
01:23Skin Diseases and Disorders
6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
01:22Burn Injuries
4.9K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
4.9K
01:30Pneumonia III: Complications and Assessment
1.1K
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.1K
01:27Acute Pyelonephritis I: Introduction
978
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
978
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
581
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
581