在上通道尿路癌症中节约脏的方法:叙述性审查
Charalampos Kefalas1, Nikolaos Datseris1, Konstantinos Sitaridis1
1Urology Department, General Hospital of Thessaloniki 'O Agios Dimitrios', Thessaloniki, GRC.
Cureus
|March 13, 2026
概括
节约性手术 (KSS) 提供了相似的存活率,以激进的nephroureterectomy上道泌尿道癌 (UTUC),保持功能. 需要进一步的研究来定义最佳的KSS协议和分子指导.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 上道泌尿道癌 (UTUC) 是一种罕见的癌症.
- 激进脏切除术 (RNU) 是标准的,但导致功能障碍.
- 节手术 (KSS) 正成为一种新兴的替代方案.
研究的目的:
- 审查最近关于UTUC脏节约技术的证据.
- 检查细化KSS患者选择的参数.
- 讨论新的和未来的KSS方法.
主要方法:
- 对UTUC的脏节约技术的文献综述.
- 对临床,放射学和分子参数进行风险分层分析.
- 对UGN-101和光动力学疗法等新型疗法的评估.
主要成果:
- 在低风险的UTUC中,内镜切除显示了与RNU相似的生存率,但复发率更高.
- 细分/整体尿切除术可保持功能,瘤结果与RNU相似.
- 新型疗法显示有前途的早期结果.
结论:
- 对于某些UTUC患者来说,KSS是RNU的可行替代品,可以保持功能.
- 术后疗法和生物标志物可能会扩大KSS的适用性.
- 长期结果和个性化治疗算法需要通过多中心研究进一步调查.
相关概念视频
Kidney Transplant II: Surgical Procedure
659
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
659
Urinary Tract Calculi VI: Surgical Management
736
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
736
Kidney Transplant I: Introduction
646
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
646
Anatomy of the Genitourinary System I: Kidneys and Ureters
917
The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
917


