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Updated: Mar 14, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Published on: February 21, 2018

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在人类红细胞前体HUDEP-2细胞中调节BCL11ADNA结合和表达

Meigen Yu, Puspa Das, John R Horton

    bioRxiv : the preprint server for biology
    |March 13, 2026
    PubMed
    概括

    BCL11A是血红蛋白切换的关键因素,也是血液疾病的治疗点. 这项研究阐明了它的DNA结合,表观遗传调节,以及小分子如何影响它的网络,提供了新的HbF重新激活策略.

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    Pan-myeloid Differentiation of Human Cord Blood Derived CD34+ Hematopoietic Stem and Progenitor Cells10:25

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