灵长类人脑外围皮层在记忆和情绪调节中的作用:本体生殖和早期侮辱
Jocelyne Bachevalier1, Alison R Weiss2
1Emory National Primate Research Center, Atlanta, GA, USA.
概括
围膜皮质对于记忆和行为调节至关重要. 它的早期发展支持识别记忆,而新生儿功能障碍影响执行功能,而不是记忆补偿.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 发育神经科学的发展神经科学.
背景情况:
- 周围大脑皮层是前叶中叶皮层的一部分,最初与严重的记忆丧失有关.
- 随后的研究揭示了它在熟悉性判断,识别记忆,执行控制和行为调节中的关键作用,与海马体角色不同.
- 现在人们认为,中叶皮层区域的损伤,包括外皮层,是以前归因于海马和杏仁体结合性损伤的记忆缺陷的原因.
研究的目的:
- 审查外围皮质与其他大脑结构的解剖学和相互联系.
- 通过对非人类灵长类动物进行的神经外科切除研究,提供关于其在成人记忆和行为中的作用的证据.
- 检查从婴儿期到成年期围内皮层的功能成熟及其对认知过程的影响.
主要方法:
- 对外围内皮层连接的解剖学研究的综述.
- 在非人类灵长类动物中进行神经外科切除研究.
- 功能成熟和对认知功能的发展影响的分析.
主要成果:
- 围膜皮质在成年非人类灵长类动物的记忆和行为调节中起着至关重要的作用.
- 它在识别记忆中的功能在婴儿早期出现.
- 新生儿外围内皮层功能障碍导致成年人在识别和工作记忆方面得到补偿,但会损害认知控制和灵活性.
结论:
- 周围大脑皮层对于熟悉性判断至关重要,与海马回忆不同.
- 它在识别记忆中的作用是在生命早期发展起来的.
- 脑外皮层的功能障碍对理解和诊断神经发育障碍 (如,阿尔茨海默氏症和精神分裂症) 有影响.
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