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Updated: Mar 14, 2026

Shotgun Lipidomics of Rodent Tissues
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Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

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POx-脂质作为PEG-脂质的替代品? 化学和结构的多方法评估

Ekaterina Tsarenko1,2, Ilya Anufriev1,3, Caroline T Holick1,2

  • 1Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743 Jena, Germany.

Analytical chemistry
|March 13, 2026
PubMed
概括

聚乙二氧化) (PEtOx) 脂质在制药配方中显示出作为聚乙烯糖醇 (PEG) 脂质替代品的希望. PEtOx-脂质体表现出与PEG-脂质体相似的水分和水力动力学尺寸,这表明它们可能是生物相容的替代品.

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A Quantitative Fluorescence Microscopy-based Single Liposome Assay for Detecting the Compositional Inhomogeneity Between Individual Liposomes09:12

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Lipid Vesicle-mediated Affinity Chromatography using Magnetic Activated Cell Sorting LIMACS: a Novel Method to Analyze Protein-lipid Interaction07:33

Lipid Vesicle-mediated Affinity Chromatography using Magnetic Activated Cell Sorting LIMACS: a Novel Method to Analyze Protein-lipid Interaction

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Lipids as Anchors

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Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
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Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
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