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Updated: Mar 14, 2026

Expression and Purification of Mammalian Bestrophin Ion Channels
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Expression and Purification of Mammalian Bestrophin Ion Channels

Published on: August 2, 2018

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βA4-晶突变破坏结构稳定性和晶相互作用在先天性白内障的发病因子

Xiaoshan Lin1, Shasha Deng2, Wenqian Li2

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China.

Investigative ophthalmology & visual science
|March 13, 2026
PubMed
概括

在β-A4-晶体蛋白中的突变通过各种机制引起先天性白内障. 阿尔法A-晶优先稳定容易聚合的突变,这表明针对这种眼睛疾病的向治疗方法.

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