在抗瘤免疫期间CD73和腺在CD8+T细胞耗尽中的对比功能

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Juan Saavedra-Almarza1, Solange Gouët1, Felipe Malgue1

  • 1Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.

Oncoimmunology
|March 13, 2026
PubMed
概括

CD73促进T细胞疲分化,而腺A2A受体信号维持瘤中的前体耗尽的T细胞. 这说明了CD73/腺轴在T细胞耗尽和抗PD-1治疗中的作用.

关键词:
在A2AR信号传输中.亚丁氨酸 (Adenosine) 是一种CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73 CD73埃克托-5′; NT NT 在线耗尽的CD8+ T细胞黑色素瘤是一种黑色素瘤.

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