对于儿科患者的后感染性脑水性病的风下道分流:系统性审查
Pedro Lucas Campos1, Kaike Lobo2, Cláudia Santos3
1Department of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil. pedrolucasiozzo@gmail.com.
概括
静脉下垂体转移 (VSGS) 为儿科后传染性水头 (PIH) 提供了暂时的脑脊液 (CSF) 转移. 本次审查强调了可变的转换率到腹腔关节 (VPS) 和显著的死亡率,强调了需要更多的研究.
科学领域:
- 儿科神经外科 儿科神经外科
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 静脉下转移 (VSGS) 是一种用于儿科后出血性水脑的临时脑脊液 (CSF) 转移方法.
- 在儿科后传染性水头 (PIH) 中VSGS的疗效和安全性尚未得到充分证实.
- 了解VSGS在PIH中的作用对于优化小儿神经外科手术治疗策略至关重要.
研究的目的:
- 系统地审查目前关于使用 Ventriculosubgaleal shunting (VSGS) 治疗儿科后传染性水头 (PIH) 的证据.
- 评估关键结果,包括转换为心室关节突变 (VPS) 和患者死亡率.
- 确定二次结果,如CSF泄漏,分流阻塞和需要修订.
主要方法:
- 在PubMed,Embase,Cochrane和Web of Science数据库中进行了系统的文献搜索.
- 包括涉及使用VSGS治疗PIH的儿科患者的研究.
- 数据分析的重点是转换到VPS,死亡率,CSF泄漏,分流阻塞和修订率,使用R统计软件进行总结.
主要成果:
- 分析了7项研究,包括6项涉及266名儿科患者的病例系列.
- 转换率为VPS的范围广泛,从50%到100%,死亡率在0%到44.4%之间.
- 报告的次要结果包括10.2%的修订,5.3%的变送阻塞和10.5%的CSF泄漏.
结论:
- 这一系统性审查是第一个专门研究小儿PIH患者VSGS的系统性审查.
- 结果中观察到显著的异质性,特别是转换到VPS和死亡率.
- 由于缺乏比较研究,需要进一步研究以澄清VSGS在PIH管理中的作用和有效性.
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