针对流行病的AI基础模型:前进的承诺,挑战和道路
Max S Y Lau1, C Jessica E Metcalf2, Zewen Liu3
1Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322.
概括
基础模型,大型人工智能系统,可以彻底改变流行病科学. 一个单一的预训练模型可以快速预测和应对跨多种病原体和环境的疫情,增强全球卫生安全.
科学领域:
- 流行病学和人工智能的人工智能
- 人工智能在公共卫生中的应用.
- 疾病建模和监测.
背景情况:
- 基金会模型正在改变科学发现,因为它们有能力学习可概括的表示.
- 流行病建模目前依赖于病原体特定的传统模型,这些模型在爆发期间难以获得快速洞察力.
- SARS-CoV-2 流行病突出了传统流行病建模的局限性.
研究的目的:
- 探索基础模型在流行病科学中的潜力.
- 对传染病动态进行单一预训练模型的可行性进行研究.
- 为了能够更快地预测,推断和应对新出现的疫情.
主要方法:
- 探索基础模型扩展到流行病科学的概念框架.
- 识别挑战,包括非静止性,碎片化数据,多样化的动态和可解释性.
- 提出了一份路线图,涉及算法创新,开放数据集和跨学科合作.
主要成果:
- 流行病的单一基础模型可以捕获病原体,种群和环境中共享的原则.
- 这种模型可以用最小的数据进行微调,以获得快速的洞察和响应.
- 应对挑战对于开发有效的流行病基础模型至关重要.
结论:
- 开发流行病的基础模型是迫切的,并且由于人工智能的进步,越来越合理.
- 这些模型为加强全球卫生安全提供了转变的机会,特别是在资源不足的环境中.
- 开发过程本身将揭示数据缺口,并指导监控投资.
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