射频与阴道雌激素治疗更年期性功能障碍:随机临床试验的系统审查和元分析
Alice F Diniz1, Mariana X Ciuffatelli2, Laura F Queiroz3
1Department of Medicine, Escola Superior de Ciências da Saúde, Brasília, DF, 70710-907, Brazil.
Sexual medicine reviews
|March 13, 2026
概括
射频 (RF) 疗法显示为与更年期 (GSM) 相关的生殖尿综合征性功能障碍的非荷尔蒙治疗有前途. 与阴道雌激素相比,射频改善了性功能得分,为寻求非荷尔蒙选择的女性提供了潜在的替代方案.
科学领域:
- 妇科 妇科 妇科 妇科
- 性医学性医学性医学性医学
- 医疗技术 医疗技术 医学技术
背景情况:
- 更年期性尿生殖综合征 (GSM) 显著影响更年期后妇女的生活质量,经常导致性功能障碍.
- 阴道雌激素是标准治疗方法,但针对特定患者群体寻求非激素替代方案.
研究的目的:
- 为了比较射频 (RF) 治疗与阴道雌激素在治疗绝经后妇女的性功能障碍时的疗效,使用GSM.
- 评估RF作为一种潜在的非荷尔蒙治疗选择.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析,将阴道RF与阴道雌激素进行比较.
- 在PubMed,Embase和Cochrane图书馆进行的搜索截至2025年6月.
- 偏见风险和证据的确定性,使用既有方法进行评估.
主要成果:
- 包括4个RCT,共156名参与者.
- 与阴道雌激素相比,射频治疗显示出女性性功能指数 (FSFI) 总得分的统计学上显著改善 (平均差异4.85;P=0.05).
- 在两个治疗方法之间,在单个FSFI领域中没有发现显著差异.
结论:
- 射频疗法是一个有前途的非荷尔蒙替代品,用于管理女性的性功能障碍与GSM.
- 需要进一步的研究来确定GSM射频治疗的长期疗效和耐用性.
更多相关视频
14:26A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
Published on: April 7, 2014
16.3K
06:18An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
13.0K
相关概念视频
Hormonal Regulation of the Menstrual Cycle
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Male Sexual Response: Erection & Ejaculation
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Menopause
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Disorders of the Male Reproductive System
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
