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Updated: Mar 15, 2026

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通过基于质谱的蛋白质组分析诊断的阿波利波蛋白A-IV心脏粉样性病

Yu Masutani1, Kenji Onoue2, Tsunenari Soeda3

  • 1Department of Internal Medicine, Nara General Medical Center, Nara, Japan; Department of Cardiovascular Medicine, Nara Medical University, Nara, Japan.

JACC. Case reports
|March 13, 2026
PubMed
概括

阿波利波蛋白A-IV氨基粉症 (AApoA-IV CA) 模仿过胺氨基粉症,但可以通过特定的组织学发现来区分. 质谱学证实AApoA-IV CA,有助于准确的诊断.

关键词:
阿波利波蛋白A-IV心脏氨基粉症电子显微镜的电子显微镜内心肌瘤活检内心肌瘤活检基于质谱学的蛋白质组分析.

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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