GDF15的上下文依赖性作用: GDF15+与瘤相关的巨细胞通过增强细胞形成来抑制OSCC的进展

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Xinyu Zhou1,2, Zhihang Zhou3, Houyu Ju1,2

  • 1Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 13, 2026
PubMed
概括

增长差异化因子15 (GDF15) 在口腔癌中起着双重作用. 虽然分泌的GDF15促进瘤,但来自巨细胞的GDF15有助于免疫反应和瘤回归,提供了新的治疗见解.

关键词:
增长差异化因子 15 15免疫检查点封锁封锁口腔状细胞癌的癌症.发酵细胞的形成 发酵细胞的形成

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