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非共价PAR结合指导蛋白质到PARP1-介导的PARylation

Arthur Fischbach1,2, Klara Bangert2, Alexander Bürkle2

  • 1Max Planck Institute for Biology of Ageing, Molecular Genetics of Ageing Department, 50931 Cologne, Germany.

ACS chemical biology
|March 13, 2026
PubMed
概括

聚ADP-ribosyl化 (PARylation) 是由蛋白质与聚ADP-ribose (PAR) 结合的方式来调节的. 不同的结合模式影响了共价PARylation的效率,影响细胞过程.

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