相关实验视频
Updated: Mar 15, 2026

08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.9K
手术神经调节:黄金葡萄球菌的流行,脱殖和感染率
Randall W Treffy1, Justin Morris1, Pranjal Srivastava2
11Department of Neurosurgery, Medical College of Wisconsin, Milwaukee; and.
Journal of neurosurgery
|March 13, 2026
概括
术前查金色葡萄球菌 (金色葡萄球菌),包括对甲素敏感的金色葡萄球菌 (MSSA) 和脱殖协议显著减少了接受内巴克洛芬的患者的手术部位感染 (SSIs). 这些策略也可能有利于接受脊髓或深度大脑刺激手术的患者.
科学领域:
- 神经外科 神经外科
- 传染性疾病 传染性疾病
- 医疗器械植入 医疗器械植入
背景情况:
- 金色葡萄球菌 (S. aureus),包括耐甲素金色葡萄球菌 (MRSA) 和对甲素敏感的金色葡萄球菌 (MSSA),在神经植入器件程序后殖民患者并构成深部手术部位感染 (SSI) 的风险.
- 深层SSI在预防和治疗方面存在独特的挑战,可能需要移除设备.
研究的目的:
- 评估手术前S. aureus殖民测试和脱殖协议在减少深层SSI方面的有效性.
- 分析MRSA和MSSA在接受脊髓刺激 (SCS),深度大脑刺激 (DBS) 和脑内巴克洛芬 (ITB) 程序的患者中殖民的患病率.
主要方法:
- 在2013年6月至2024年6月期间进行的513个SCS,1050个DBS和414个ITB程序的前性维护数据库的回顾性分析.
- 评估手术前的S. aureus鼻拭子结果,手术后的SSI (表面和深层),设备的移除,以及患者的并发症.
- 评估各种外科手术期间的殖民查,脱殖和抗生素协议.
主要成果:
- 在大约20%的SCS/DBS患者和25%的ITB患者中发现了S. aureus殖民.
- 在所有手术类型中,MSSA殖民比MRSA殖民更为普遍.
- 在实施手术前去殖民化方案后,ITB组的感染率从8%降至2%以下. 在SCS组中没有观察到深度SSI.
结论:
- 对于接受神经植入器械手术的患者,特别是ITB的患者,建议对MRSA和MSSA进行手术前查,因为仅MRSA查就错过了S. aureus殖民的很大一部分.
- 在手术前实施脱殖协议可以显著减少ITB接收者的SSIs.
- 这些发现表明,黄金色细菌查和脱殖协议也可能减少SCS和DBS程序中的SSIs.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
4.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.7K
Factors Affecting the Risk of Infection
14.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.5K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
6.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.4K
Inflammatory Bowel Disease V: Surgical Management
803
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
803
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
950
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
950

