ReEnSta通过减少术后胀和开放手术后血静止来缓解疼痛
Bitna Kweon1, Junsang Yoo2, Hyun Soo Shim2
1Department of Pharmacology, School of Korean Medicine, Wonkwang University, Iksan, Republic of Korea; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan, Republic of Korea.
The Journal of surgical research
|March 13, 2026
概括
韩国草药配方ReEnSta显著减少了小鼠的术后胀和疼痛. 这种自然疗法通过减少炎症和伤,有助于恢复.
科学领域:
- 草药是一种草药.
- 药理学 药理学 是一个学科.
- 术后恢复 术后恢复
背景情况:
- 手术后的胀,疼痛和延迟恢复是手术创伤后的常见问题.
- 传统的东亚草药是用来改善血液循环和减少血停滞的.
- 瑞恩斯塔 (ReEnSta) 是韩国的一种草药配方,含有Prunus persica种子,Carthamus tinctorius,Paeonia suffruticosa,以及Massa Medicata Fermentata. 这种配方是韩国制造的.
研究的目的:
- 评估ReEnSta在缓解术后胀,疼痛和炎症方面的疗效.
- 研究ReEnSta对微血管出血和炎症标志物的影响.
主要方法:
- 在小鼠中,通过后爪切口诱导术后胀.
- ReEnSta是口服的,剂量各不相同 (低,中,高).
- 评估结果包括脚胀,机械体,运动活动,铁沉积和炎症性细胞因子mRNA表达.
主要成果:
- ReEnSta显著降低了脚的胀,在中间剂量时观察到最佳的降低 (在第14天降低高达69.1%).
- 机械体被减弱,组织学铁沉积被ReEnSta显著减少.
- 瘤亡因子-α (Tnf-α) mRNA表达被抑制,特别是在中间剂量时,对体重或活动没有不良影响.
结论:
- ReEnSta有效地缓解了术后的胀,伤和疼痛.
- 该机制涉及减少微血管出血和炎症反应.
- ReEnSta显示出作为一种安全的草药治疗或功能性食品的潜力,用于增强术后恢复.
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