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Updated: Mar 15, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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在人工智能时代,对G蛋白结合受体进行计算机辅助的结构建模和药物发现

Sabina Novack1, Marta Filizola1

  • 1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, 10029, USA.

Current opinion in structural biology
|March 13, 2026
PubMed
概括

人工智能 (AI) 正在通过增强结构预测和药物设计来彻底改变G蛋白结合受体 (GPCR) 研究. 这些人工智能应用正在加速针对GPCRs的新药的发现.

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