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Updated: Mar 15, 2026

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发现和描述类固醇衍生物作为hCES2A抑制剂

Yueyang Cao1, Jiayi Luo1, Yong Yang2

  • 1State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.

Bioorganic & medicinal chemistry
|March 13, 2026
PubMed
概括

一种新型的类固醇衍生物,化合物3g,有效地抑制人类的碳素酶2A (hCES2A),这是药物代谢中的关键酶. 这种强效和选择性抑制剂在管理化疗副作用方面表现有前途.

关键词:
具有竞争力的抑制剂.人类的碳氧乙酶2A.抑制剂 抑制剂 抑制剂类固醇衍生品类固醇衍生品结构活动关系结构活动关系

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