周围神经损伤对烧伤结果的影响 烧伤护理质量平台
Elizabeth Blears1, Sharon Shania2, Jagger Godarzi2
1Department of Plastic and Reconstructive Surgery, Tower Health-Reading Hospital, 420 S 5th Ave, West Reading, PA 19611, USA.
概括
烧伤患者的外围神经损伤 (PNI) 会增加皮肤移植损失和住院时间. 虽然PNI与不良结果有关,但在本研究中,它不是死亡率的独立预测因素.
科学领域:
- 创伤外科 手术 创伤外科
- 神经外科 神经外科
- 烧伤护理研究研究
背景情况:
- 在烧伤患者中,外围神经损伤 (PNI) 的影响,包括疼痛和缺陷,尚未得到充分研究.
- 烧伤护理质量平台 (BCQP) 是一个全球数据库,用于烧伤患者的结果,包括PNI率.
- 没有先前的研究分析了使用BCQP的PNI对烧伤结果的影响.
研究的目的:
- 调查外围神经损伤 (PNI) 与烧伤患者的结果之间的关联.
- 确定PNI是否可以独立预测皮肤移植损失,住院时间和死亡率等不良结果.
主要方法:
- 利用2000-2022年BCQP的疾病国际分类代码来识别烧伤患者的PNI.
- 排除了先前存在的神经病变或中枢神经损伤的患者.
- 采用二项逻辑和线性回归来分析PNI对燃烧结果的影响,控制人口和燃烧特征.
主要成果:
- 在BCQP中,0.7%的烧伤患者经历了PNI.
- 患有PNI的患者显著增加了皮肤移植损失的风险 (OR:4.1) 和更长的住院时间 (OR:7.2).
- 经过多变量调整后,PNI与外科手术的数量略有增加 (OR:0.8),但与死亡率无关.
结论:
- 周围神经受伤与烧伤患者的不良结果独立相关,包括较高的皮肤移植损失率和长时间的住院治疗.
- 当调整以考虑混因素时,PNI不是烧伤患者死亡率的独立预测指标.
- 需要进一步的研究,以改善烧伤病例中外围神经损伤后的患者结果.
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