儿科和成人群体的光学连贯性断层扫描血管学:综合性综述
Anna M Busza1, Clayton E Lyons1, Nikoo Hamzeh1
1Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Survey of ophthalmology
|March 13, 2026
概括
年龄影响光学连贯断层扫描血管学 (OCT-A) 度量,显示成年人黄斑血管密度下降,但儿童的变化可变. 在各个年龄组中,状血管区域的大小保持稳定.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 生物标志物 生物标志物
背景情况:
- 光学连贯断层扫描血管造影 (OCT-A) 是一种非侵入性的视网膜成像技术.
- 作为系统性疾病的生物标志物,OCT-A具有潜力.
- 老龄化对OCT-A参数的影响需要进一步阐明.
研究的目的:
- 全面审查和综合现有关于年龄对OCT-A参数影响的文献.
- 在不同人群中识别视网膜血管结构的与年龄相关的变化.
- 为儿科和老年成年人群建立规范性CT-A值.
主要方法:
- 在七个数据库中进行系统的文献审查.
- 选了271篇全文文章,其中156篇符合纳入标准.
- 提取人口统计数据,研究设计,OCT-A设备以及斑点和视神经头部区域的测量参数.
主要成果:
- 在成年人中观察到与年龄相关的斑点血管密度的持续下降,独立于信号强度.
- 在儿科研究中观察到的年龄和血管参数之间的可变关联.
- 在所有被研究的人群中,状血管区域的大小显示了与年龄相关的最小变化.
结论:
- 年龄是影响OCT-A指标的关键因素,特别是成年人的斑点血管密度.
- 在临床和研究环境中解释OCT-A发现必须考虑到患者的年龄.
- 进一步的研究可能会改进特定年龄的规范性OCT-A值,以提高诊断准确度.
相关概念视频
Imaging Studies for Cardiovascular System V: CT
486
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
486
Imaging Studies VII: Vascular Imaging
441
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
441
Computed Tomography
9.3K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.3K
Imaging Studies III: Computed Tomography
558
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
558
Radiological Investigation III: Pulmonary Angiogram and PET Scan
600
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
600
Imaging Studies for Cardiovascular System IV: CMRI
463
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
463


