提高人类乳头瘤病毒疫苗接种率在圆环电外科切除手术 (LEEP) 后在结肠镜检查:质量改善研究
Jordan A Lewis1, Stacey Foote2, Elizabeth Cooper2
1The University of British Columbia, Department of Obstetrics and Gynaecology.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
|March 13, 2026
概括
在LEEP治疗宫发育不良后,辅助性HPV疫苗接种显著增加了26.8%的疫苗接种率. 干预发现成本和时间是高风险患者HPV疫苗接种的关键障碍.
科学领域:
- 妇科 妇科 妇科 妇科
- 在瘤学瘤学.
- 疫苗学 疫苗学 疫苗学
背景情况:
- 在LEEP后的辅助性HPV疫苗接种显示出减少宫内皮质瘤2+复发的前景.
- 接受LEEP的高风险患者群体代表了干预的关键窗口.
研究的目的:
- 在接受LEEP的患者中,在六个月内将HPV疫苗接种率提高15%.
- 在这个队列中确定患者报告的HPV疫苗接种障碍.
主要方法:
- 一个中断的时间序列质量改善研究,涉及127名年龄在24-45岁的患者进行首次LEEP.
- 干预措施包括护士主导的教育和Gardasil-9处方的提供.
- 主要结果:六个月的疫苗接种率;过程措施:处方/小册子发行;平衡措施:成本,疫苗反应.
主要成果:
- 在6个月内,HPV疫苗接种率从42.5%增加到69.3% (绝对增加26.8%).
- 在随访中观察到的患者中,47.9%开始接种疫苗系列.
- 接种疫苗的主要障碍是成本 (32.4%) 和时间限制 (23.3%).
结论:
- 在接受LEEP的患者中,协作干预有效地提高了HPV疫苗接种率.
- 这一战略为宫癌预防的参与提供了一个重要的机会.
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