Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Ras Gene02:38

The Ras Gene

The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Chlorella vulgaris and Lactobacillus casei Combination Therapy Attenuates Testicular Endoplasmic Reticulum Stress and Dysfunction in a C57BL/6 Mouse Model of NAFLD.

Probiotics and antimicrobial proteins·2026
Same author

CRISPR/Cas9-mediated knockout of TopBP1 shifts the Bax/Bcl-2 balance toward apoptosis in MCF7 breast cancer cells.

Molecular biology reports·2026
Same author

Novel Insights into Pontocerebellar Hypoplasia Type 3: Discovery of a New Disease-causing PCLO Variant and Development of a CRISPR-generated Cell Model : Novel Insights into Pontocerebellar Hypoplasia Type 3.

Galen medical journal·2026
Same author

Mismatch Repair Proteins and CD45RO-Positive Lymphocytes in Malignant and Benign Salivary Gland Tumors: A Favorable Association with Disease Clinical Parameters.

International archives of otorhinolaryngology·2026
Same author

Correction to: Assessing the Impact of Collagenase Clostridium histolyticum Injection on Biomechanical Properties of Uterine Fibroids and Adjacent Myometrial Tissue.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same author

Evaluation of serum NEAT1 and MALAT1 expression as diagnostic biomarkers in tyrosinemia, a rare metabolic disorder.

Orphanet journal of rare diseases·2026

相关实验视频

Updated: Jun 25, 2026

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

8.9K

声息肉和雷因克瘤之间的基因表达差异

Kamyar Iravani1, Negar Azarpira2, Mahintaj Dara3

  • 1Department of Otolaryngology, Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

The Laryngoscope
|March 13, 2026
PubMed
概括

基因表达分析揭示了声多和雷因克瘤的不同模式. 这项研究有助于区分这些良性声带病变,并了解其潜在原因.

关键词:
雷因克的胀 雷因克的胀原蛋白是一种原蛋白.纤维肌肉生殖细胞基因表达的基因表达方式互乐金是一种介质蛋白.矩阵金属蛋白质酶 (MTPA) 是一个发声的多胞体.

更多相关视频

Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

9.7K
Hemi-laryngeal Setup for Studying Vocal Fold Vibration in Three Dimensions
10:13

Hemi-laryngeal Setup for Studying Vocal Fold Vibration in Three Dimensions

Published on: November 25, 2017

11.6K

相关实验视频

Last Updated: Jun 25, 2026

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

8.9K
Construction and Characterization of a Novel Vocal Fold Bioreactor
11:11

Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

9.7K
Hemi-laryngeal Setup for Studying Vocal Fold Vibration in Three Dimensions
10:13

Hemi-laryngeal Setup for Studying Vocal Fold Vibration in Three Dimensions

Published on: November 25, 2017

11.6K

科学领域:

  • 耳鼻喉科 耳鼻喉科 耳鼻喉科
  • 分子生物学分子生物学
  • 遗传学 是一个遗传学.

背景情况:

  • 声的息肉和雷因克的瘤是良性声带病变,具有相似的组织结构,但有不同的原因.
  • 由于重叠的组织学特征,准确的诊断具有挑战性.

研究的目的:

  • 为了研究雷因克水和声多之间的基因表达差异.
  • 提高诊断能力,了解这些病变的病理生理学.

主要方法:

  • 一项横截面研究分析了手术内声组织样本.
  • 用RT-qPCR比较六个关键基因 (COL1A1,COL3A1,FN1,MMP-9,IL-8,IL-1β) 的mRNA表达.
  • 对多次比较应用了错误发现率 (FDR) 校正.

主要成果:

  • 与雷因克水相比,声的息肉中COL1A1,FN1和MMP-9的调节显著上升 (q <0.01).
  • 在FDR校正后,COL3A1,IL-1β和IL-8显示出非显著的差异.

结论:

  • 在炎症和细胞外基因基因中,不同的基因表达特征区分了声聚体和雷因克水.
  • 这些发现可能有助于诊断,并提高对病变病因学的理解.
  • 建议使用更大的样本大小和健康对照进行进一步验证.