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在过阶段对偏磁边缘病变的优异可见性与SWI相比

Joshua D Lee¹, Brian Renner¹, Sreekanth Madhusoodhanan Nair¹

¹From the Cedars-Sinai (J.D.L., B.R., S.M.N., E.L., N.L.S., P.S.), 8700 Beverly Blvd, Los Angeles, CA, 90048, USA; Cleveland Clinic, 9500 Euclid Ave (K.N.D.O.), Cleveland, OH, 44195, USA; University of Pennsylvania (R.T.S.), Philadelphia, PA, 19104, USA; National Institute of Neurological Disorders and Stroke (D.S.R.), National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA; Larner College of Medicine at the University Of Vermont (A.J.S.), Burlington, VT, 05401, USA and Appendix.

AJNR. American journal of neuroradiology

|March 13, 2026

概括

过的相位图像,而不是标准的SWI,对于检测偏磁边缘病变 (PRL),多发性硬化症 (MS) 的关键生物标志物更优越. 这一发现有助于在临床实践中准确诊断和评估MS.

科学领域:

放射学放射学是一门学科.
神经成像是一种神经成像.
生物标志物生物标志物

背景情况:

偏磁边缘病变 (PRL) 是多发性硬化症 (MS) 的一个特定的成像生物标志物.
PRL被纳入了2024年麦当劳的MS诊断标准.
可以使用标准敏感度加权成像 (SWI) 或单独相位图像来可视化PRL.

研究的目的:

为了比较PRL在SWI上的可见性与相位图像.
在临床环境中确定PRL评估的最佳成像对比度.

主要方法:

分析了疑似多发性硬化病例的两个横截面队列 (n=40).
包括SWI在内的脑MRI是在3T获得的.
T2高强度病变被盲目评定者在SWI和相位图像上分类为PRL或非PRL.

主要成果:

阶段图像检测出明显更多的PRL比SWI (152比89在聚合队列中,p<0.001).
66 (42.6%) 的PRL仅在相位图像上被识别出来.
在SWI上非PRL分类的原因包括结节的外观和不连续的边缘.

结论:

来自SWI的过相位图像优于用于PRL识别的增强大小图像.
阶段图像应该是临床实践中用于MS诊断的PRL评估的主要选择.

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