在普通肉类,低肉类,鱼类和素食饮食模式的生物衰老:基于人口的队列研究
Chuan-Rui Zeng1, Yang-Wei Cai2, Mao-Xiong Wu1
1Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
植物性饮食,包括素食和鱼类饮食模式,与定期肉类消费相比,与较慢的生物衰老有关. 这些饮食选择可能会促进更健康的衰老,并降低与年龄有关的疾病风险.
科学领域:
- 营养科学 营养科学
- 老年学是指老年学的学科.
- 遗传学 是一个遗传学.
背景情况:
- 饮食是影响健康和寿命的关键可修改因素.
- 关于饮食模式与生物衰老之间的关联的证据有限.
- 了解这种联系对于促进健康衰老至关重要.
研究的目的:
- 调查饮食模式与生物衰老加速之间的横截面和纵向关联.
- 分析大量基于人口的队列数据.
主要方法:
- 包括407,376名基线参与者和8,855名随访者.
- 将饮食分为经常吃肉的人,少吃肉的人,吃鱼的人和素食主义者.
- 使用克莱梅拉-杜巴尔方法 (KDM-BA) 和表型年龄 (PhenoAge) 估计的生物年龄加速.
主要成果:
- 低肉类,鱼类和素食饮食与与常规肉食者相比显著较低的生物衰老加速有关.
- 吃鱼的人显示KDM-BA加速的最大减少 (β = -2.47),其次是素食者 (β = -2.34) 和低肉食者 (β = -0.61).
- 纵向分析显示,在低肉,鱼或素食饮食的参与者中,生物年龄加速较慢.
结论:
- 植物性饮食 (含鱼或不含鱼) 和低肉饮食与较慢的生物衰老有关.
- 减少肉类和适度食用鱼类可能是健康衰老的可行策略.
- 这些饮食模式可以减轻与衰老相关的疾病的负担.
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