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Updated: Mar 15, 2026

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开发和评估作为EPAC1激活剂的福氧乙酸化合物

David Morgan1, Jolanta Wiejak2, Frederick G Powell1

  • 1Institute of Chemical Sciences, Heriot-Watt University, Riccarton, Edinburgh EH14 4AS, U.K.

Journal of medicinal chemistry
|March 14, 2026
PubMed
概括

新的黄酸作为非核酸激动剂,直接通过cAMP 1 (EPAC1) 激活Exchange蛋白. 这些化合物显示出作为抗纤维素剂的潜力,具有良好的安全性.

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