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Updated: Mar 15, 2026

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肝细胞SLCO4C1是抑制脂质生成的cAMP吸收载体,也是MASLD治疗点

Xiaojia Huang1, Sen Liang1, Nan Zhao1

  • 1Department of Gastroenterology, Institute of Digestive Diseases of PLA, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Medical Research Center, Cholestatic Liver Diseases Center, The First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.

Nature communications
|March 14, 2026
PubMed
概括

与代谢功能障碍相关的脂肪性肝病 (MASLD) 涉及上调的SLCO4C1,一种抑制脂肪积累的cAMP载体. 增强SLCO4C1活性显示出对治疗MASLD的前景.

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