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Updated: Mar 15, 2026

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line
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一个本体生成-细胞因子代码决定了巨细胞反应极性和瘤结果

Dominik J Schaer1, Nadja Schulthess-Lutz1, Matthias J Peterhans1

  • 1Department of Internal Medicine, University Hospital and University of Zurich, Zurich, Switzerland.

Communications biology
|March 14, 2026
PubMed
概括

巨细胞在癌症中的功能取决于发育起源 (本能) 和细胞因子信号,而不仅仅是M1/M2状态. 这种本体生成-细胞因子框架指导向的癌症免疫疗法.

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