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平衡液体玻尿酸:我们应该更喜欢平衡的晶化物而不是"正常"的盐水吗?
Kelsey Carrigan1, Satyan Lakshminrusimha2
1Department of Pediatrics, Division of Neonatology, UC Davis Children's Hospital, Sacramento, CA, USA. kcarrigan@health.ucdavis.edu.
概括
新生儿的液体复苏缺乏基于证据的指导. 均衡的晶体化物可能比正常的盐水更安全,可能减少新生儿重症监护室 (NICU) 中的急性损伤和代谢性酸.
科学领域:
- 新生儿复苏新生儿的复苏
- 儿科重症监护 儿科重症监护
- 静脉注射液体疗法是一种静脉注射液体疗法.
背景情况:
- 液体玻尿酸对于纠正新生儿的低 perfusion,低血压和代谢性酸性疾病至关重要.
- 0.9%的化 (普通盐水) 是最常见的液体,但有证据将其与不良结果联系起来.
- 成年人的研究表明,平衡的晶体质可能优于正常的盐水.
研究的目的:
- 审查在新生儿中使用平衡晶体的证据.
- 讨论这些挑战,并提出在新生儿重症监护室 (NICU) 选择液体的实用方法.
- 突出了新生儿流体疗法的进一步研究的需要.
主要方法:
- 关于静脉注射液体的成人和新生儿研究的文献综述.
- 讨论流体类型之间的生理差异.
- 关于新生儿流体选择临床方法的建议.
主要成果:
- 正常的盐水与高性代谢酸症和新生儿急性损伤有关.
- 平衡的晶体溶液可能由于其更生理性的组成而具有优势.
- 有限的直接证据表明平衡晶化物在新生儿中使用.
结论:
- 目前用于新生儿复苏的液体选择并非基于强有力的证据.
- 均衡的晶体化物值得考虑作为新生儿重症监护室中正常盐水的替代品.
- 更多的研究是必要的,以建立最佳的流体治疗新生儿低 perfusion 和酸性病.
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