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Updated: Mar 15, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
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编码为HIV-1的圆形RNA通过Tat结合增强病毒转录

Prisca Obi1, Lichong Yan1, Adela Dujsikova1

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

Nature microbiology
|March 14, 2026
PubMed
概括

研究人员发现了一种由HIV-1编码的新型循环RNA (circRNA),命名为circHIV. 这种病毒性circRNA通过与Tat蛋白相互作用来增强HIV-1的转录,从而促进病毒病原性.

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