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Updated: Mar 15, 2026

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
09:00

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

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等离子体通过插入序列介导的基因失活促进抗微生物耐药性

Jorge Sastre-Dominguez1,2, Paloma Rodera-Fernandez1,2, Javier DelaFuente1

  • 1Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Cientificas (CSIC), Madrid, Spain.

Nature microbiology
|March 14, 2026
PubMed
概括

携带插入序列 (IS) 的等离子体通过不激活基因在细菌中加速抗微生物耐药性 (AMR). 这项研究揭示了等离子体不仅通过传播抗药性基因来促进AMR,而且还通过IS介导的基因破坏来促进AMR.

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