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Updated: Mar 15, 2026

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
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Purification of Ubiquitinated p53 Proteins from Mammalian Cells

Published on: March 21, 2022

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由MDM2对MEIS1的乌比基化作为p53稳定和DNA损伤反应激活的开关

Jiaxin Liu1,2, Yanxia Duan1, Qing Xiao3

  • 1Department of Pathology, Xiangya Hospital, XiangYa School of Basic Medical Sciences, Central South University, Changsha, China.

Cell death and differentiation
|March 14, 2026
PubMed
概括

MDM2针对MEIS1进行降解,但MEIS1充当诱,保护p53. 准MEIS1的无处置可能会恢复p53的瘤抑制.

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