导管导向的硬化疗法与手术切除大卵巢内膜瘤之间的比较:一项回顾性,单中心的观察性研究
Yun Soo Chung1,2, Hae-Rim Kim3, Jin Kyung Baek1,2
1Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Journal of clinical medicine
|March 14, 2026
概括
乙醇导管导向性硬化疗法 (CDS) 比手术更好地保护卵巢储备. 这种微侵袭性治疗对抗米勒尔激素水平较低的妇女来说是有前途的.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 最少侵入性的妇科手术
背景情况:
- 子宫内膜异位症的治疗方法各不相同,而卵巢储备的保护是一个关键问题.
- 乙醇导管导向硬化疗法 (CDS) 正在被探索作为大型卵巢内膜瘤手术的替代方案.
研究的目的:
- 为了比较CDS与手术切除大卵巢内膜瘤 (>10厘米) 的疗效.
- 评估对卵巢储备,囊大小和癌症抗原125 (CA-125) 水平的影响.
主要方法:
- 在84名患有卵巢内膜瘤>10厘米的患者进行了回顾性单中心研究.
- 进行CDS的15名患者和进行腹腔镜卵巢囊切除/卵巢切除的69名患者之间的比较.
- 在治疗后六个月对抗穆勒尔激素 (AMH),囊大小和CA-125的变化进行评估.
主要成果:
- 与手术相比,CDS在匹配组中导致抗穆勒尔激素 (AMH) 水平的降低较小 (-0.13 ng/mL),而手术 (-0.59 ng/mL).
- 手术治疗减少了囊大小到0厘米和CA-125从62.10到11.20U/mL.
- CDS将囊大小减少到3.30厘米,CA-125从74.20升至17.60U/mL.
结论:
- 导管导向的硬化疗法在保持卵巢储备方面比手术治疗大卵巢瘤更有效.
- 对于 AMH 低水平的患者来说,CDS 是一个有前途的选择.
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