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鼻腔粘膜上皮质黑色素瘤与快速骨基础和轨道进展

Vita Konopecka^1,2, Mārtiņš Blumbergs³, Ingus Vilks^2,3

¹Bauska Hospital, Darza Street 7/1, LV-3901 Bauska, Latvia.

Journal of clinical medicine

|March 14, 2026

概括

鼻粘膜黑色素瘤可以快速入侵骨底部和轨道后手术,即使在清晰的初始成像. 早期的息治疗和出血控制对于快速进展的侵袭性瘤至关重要.

科学领域:

在瘤学瘤学.
耳鼻喉科耳鼻喉科耳鼻喉科
神经外科神经外科

背景情况:

鼻粘膜黑色素瘤是一种罕见的,具有高复发率和低生存率的侵袭性癌症.
快速的骨基和轨道进展可能发生,通常被手术前成像低估.

研究的目的:

报告一种具有侵略性的术后进展的鼻腔粘膜上皮质黑色素瘤病例.
为了突出临床过程,管理挑战和本病理学特征.

主要方法:

一名患有鼻黑色素瘤的60岁妇女接受了成像 (MRI,CT,PET-CT) 和内切除.
活检显示了具有高Ki-67增殖指数的上皮状黑色素瘤.

主要成果:

术后成像显示了大规模的骨底部破坏和视力损失的轨道入侵.
尽管接受了息性放射治疗,但患者的病情迅速下降,并在治疗后4.5个月死亡.

结论:

在鼻腔粘膜上皮质黑色素瘤中,尽管手术前成像有限,但仍可能发生 fulminant 局部进展.
优先考虑结构化息,出血控制和快速视力丧失或持续透的疼痛管理.

关键词:

轨道的延伸轨道的延伸鼻腔粘膜上皮质类黑色素瘤骨基地入侵骨基地入侵

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