认知功能与肝硬化患者的平衡,疲劳和身体活动水平之间的关系
1Department of Physical Medicine and Rehabilitation, Turgut Ozal Medical Center, İnonu University, Malatya 44280, Turkey.
Healthcare (Basel, Switzerland)
|March 14, 2026
概括
肝硬化患者的认知功能与静态平衡和疲劳有关,但与动态平衡或体力活动无关. 疾病的持续时间和运动习惯会影响认知功能和平衡.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 肝硬化逐渐损害肝细胞,影响患者的福祉.
- 已知的影响包括认知功能下降,平衡,体力活动和疲劳增加.
- 在肝硬化患者中,这些因素之间的确切关系仍未得到充分探索.
研究的目的:
- 研究肝硬化患者的认知功能与平衡,体力活动和疲劳之间的关联.
- 为潜在的治疗策略提供新的见解.
主要方法:
- 132名肝硬化患者参与了这项研究.
- 使用蒙特利尔认知评估 (MoCA) 尺度评估认知功能.
- 通过一腿姿势测试和定时上升和去测试测量平衡.
- 用国际体育活动规模简单表格评估的体育活动.
- 使用疲劳严重程度尺度评估疲劳严重程度.
主要成果:
- 认知功能 (MoCA) 与静态平衡 (r=0.232,p=0.007) 和疲劳严重程度 (r=-0.297,p=0.001) 有显著的相关性.
- 在认知功能和动态平衡 (r=-0.068,p=0.441) 或体力活动 (r=-0.011,p=0.903) 之间没有发现显著的关联.
- 疾病持续时间和运动习惯独立预测认知功能;疾病持续时间也预测静态平衡.
结论:
- 在肝硬化中,认知功能,静态平衡和疲劳严重程度之间存在显著的联系.
- 没有发现与动态平衡或体力活动有重大联系.
- 研究结果表明,认知状态在临床上与评估肝硬化中平衡和疲劳有关,尽管这些关系是关联性的,而不是因果关系.
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