在疑似肺癌的CT导向肺活检期间,肺出血和肺胸风险
Rosa Alba Pugliesi1, Nour Maalouf2, Giuseppe Gullo3
1Section of Radiology, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.
Cancers
|March 14, 2026
概括
肺出血可能会降低CT导向肺活检癌症后的肺胸风险. 这种保护作用在较深的病变中显得更强大,这表明在管理并发症方面存在潜在的益处.
科学领域:
- 肺部医学 肺部医学
- 干预性放射学 干预性放射学
- 在瘤学瘤学.
背景情况:
- 通过CT指导的肺活检对于诊断肺癌至关重要.
- 肺胸炎 (PTX) 是肺活检后的一个常见并发症.
- 肺出血是另一种潜在的活检后并发症.
研究的目的:
- 在CT导向肺活检后调查肺出血和PTX之间的关联.
- 确定病变深度是否影响出血和PTX之间的关系.
- 在接受癌症肺部活检的患者中确定PTX的预测因子.
主要方法:
- 对118名接受CT指导肺活检的患者进行了回顾性分析.
- 对PTX和肺出血的立即活检后CT的评估.
- 多变量后勤回归和相互作用分析,以评估预测因素和根据损伤深度对效应的修改.
主要成果:
- PTX发生在22.0%的活检中,肺出血发生在29.7%的活检中.
- 在患有肺出血的患者中,PTX的频率明显低 (p = 0.021).
- 一个趋势表明肺出血是保护性的 (OR 0.33),而出血深度相互作用接近显著性 (p = 0.065).
结论:
- 肺出血可能与CT导向肺活检后PTX风险降低有关.
- 这种减轻出血对PTX风险的影响可能在更深层的肺病变中更加明显.
- 研究结果表明,出血可能在减少活检相关并发症方面发挥作用.
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