在叶状乳腺癌中进行术后MRI监测的理由
Lora Grbanović1, Lucija Kovačević1, Ana Smolić2
1Department of Radiology, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
侵袭性叶状腺癌患者的新乳腺癌发病率较高. 手术后的MRI检测出乳房扫描遗漏的恶性瘤,这表明它对ILC随访有好处.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 病理学 病理学 病理学
背景情况:
- 手术后的乳腺癌监测通常使用乳房影像,在某些情况下使用MRI.
- 侵袭性叶状癌 (ILC) 呈现出独特的检测挑战和复发模式.
- 组织学类型在指导术后成像随访中的作用需要进一步调查.
研究的目的:
- 为了确定组织学类型是否可以指导术后MRI监测乳腺癌.
- 评估在解释术后成像方面读者之间的共识.
- 评估与瘤特征相关的新乳腺恶性瘤的时间.
主要方法:
- 77名患有侵袭性乳腺癌的患者的一项回顾性单中心研究 (2015-2016).
- 纳入标准:手术,治疗前和后的MRI,≥7年的随访.
- 两位放射科医生对术后MRI进行独立审查;使用科恩卡帕评估的读者间一致性.
主要成果:
- 六名患者 (8%) 患有新的乳腺恶性瘤;侵袭性叶状癌的发病率较高 (p=0.04).
- 在ILC患者中,MRI检测出了所有新的恶性瘤,而乳房镜错过了三分之二.
- 完整的读者间协议 (κ=1.00) 对于MRI和乳房镜检测.
结论:
- 患有原发性侵袭性叶膜癌的患者表现出更高的新乳腺恶性瘤的发生率.
- 手术后的MRI是有效的检测新的恶性瘤被遗漏的乳房图像在ILC.
- 瘤组织学,特别是ILC,对于定制术后监测策略具有重要意义,可能受益于MRI随访.
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