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针对癌症相关认知障碍的多学科综合性生存计划的有效性:一项前性队列研究
Nathalie Vanlaer1, Camille Testaferrata1, Lynn Decabooter1
1Department of Medical Oncology, Vrije Universiteit Brussel (VUB), Translational Oncological Research Centre, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium.
Cancers
|March 14, 2026
概括
综合神经认知修复疗法 (INCRT) 显著改善了癌症幸存者的认知功能和日常生活. 这种多学科计划还减少了痛苦和疲劳,治疗后观察到持久的好处.
科学领域:
- 神经科学是一个神经科学.
- 在瘤学瘤学.
- 心理学 心理学 心理学
背景情况:
- 与癌症相关的认知障碍 (CRCI) 对幸存者的生活质量和日常功能产生负面影响.
- 在癌症护理中,CRCI经常被忽视,尽管同时出现疲劳和痛苦等症状.
- 为了应对CRCI的复杂性质,需要采用多模式的方法.
研究的目的:
- 评估综合性神经认知修复疗法 (INCRT) 计划对CRCI癌症幸存者的有效性.
- 评估INCRT对神经认知功能,心理困扰,疲劳和日常功能的影响.
主要方法:
- 该研究涉及患有CRCI的癌症幸存者,在基线,干预后和6个月后续对其进行评估.
- 神经心理学测试和患者报告的结果测量了客观/主观的神经认知功能 (NCF),痛苦,疲劳和日常功能.
- 线性混合模型被用来分析随时间变化的结果.
主要成果:
- 客观和主观NCF在干预后和随访时显著改善 (p < 0.001).
- 随着时间的推移,心理困扰,疲劳和无助的元认知显著下降 (p <0.05).
- 参与者报告了增强的情绪/认知洞察力和改善的日常功能.
结论:
- 在癌症幸存者中,INCRT有效地改善认知功能,减少痛苦和疲劳,并提高癌症幸存者的日常功能.
- 在6个月的随访后,INCRT的益处持续.
- 该计划的整合性设计促进战略的内部化和应用,以获得持久的效果.
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