干细胞在肌肉骨组织中的应用研究景观:一个范围审查

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Updated: Mar 15, 2026

Isolating Stem Cells from Soft Musculoskeletal Tissues

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

Aiyarin Kittilukkana^1,2,3, Puwapong Nimkingratana⁴, Dumnoensun Pruksakorn^1,4

¹Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

|March 14, 2026

概括

这篇评论绘制了骨科干细胞治疗的地图,发现骨髓干细胞最常见. 它强调了趋势和差距,以指导未来的再生医学研究和临床应用.

科学领域:

整形外科整形外科整形外科
再生医学是一种再生医学.
干细胞疗法是一种干细胞疗法.

背景情况:

干细胞治疗是再生医学的关键,骨科应用越来越多.
该场是碎片化的,显示细胞类型,输送和目标的变化.
需要一个整合的概述来弥合临床前和临床研究.

研究的目的:

综合500项关于骨科干细胞治疗的临床前和临床研究的证据.
识别现有做法,新兴趋势和该领域的关键差距.
为设计安全,有效和可扩展的骨科再生疗法提供参考.

主要方法:

对500项临床前和临床研究进行范围审查.
系统的搜索和PRISMA-ScR选. 这是一个非常好的方法.
提取关于细胞类型,来源,输送,点组织和疾病指征的数据.

主要成果:

最常使用的是来自骨髓的自主介质干细胞.
脂肪和围产期衍生的干细胞越来越突出.
小动物模型 (老鼠,子) 和膝关节骨关节炎是主要研究重点.
关节内注射是主要的输送方法.

结论:

本综述绘制了目前骨科干细胞治疗实践的地图.
它确定了关键趋势,转化途径和研究差距.
提供了指导未来骨科再生医学发展的证据.

关键词:

基于细胞的疗法.介质细胞干细胞介质细胞干细胞肌肉骨系统疾病的疾病.骨科骨科医生骨科医生再生医学是一种再生医学.范围审查范围审查审查

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