作为血管光滑肌细胞骨质分化和血管化的调解者,TMAO触发的内皮-介质细胞过渡和微囊释放是血管光滑肌细胞骨质分化的调解者

Joumana Al Akhdar1, Melike Nur Yangın Yılmaz1, Kemal Baysal2,3

  • 1Graduate School of Health Sciences, Koç University, 34450 Istanbul, Türkiye.

Cells
|March 14, 2026
PubMed
概括

肠道微生物的代谢物Trimethylamine-N-oxide (TMAO) 在细胞中触发了内皮-介质酶过渡 (EndMT). 这些细胞的外体促进血管光滑肌细胞 (VSMC) 化,这是心血管疾病的关键因素.

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