使用DE-SAMNet模型对多类肺癌分类进行Grad-CAM增强可解释的深度学习
Murat Kılıç1, Merve Bıyıklı1, Abdulkadir Yelman2
1Turgut Ozal Medical Center, Department of Thoracic Surgery, Faculty of Medicine, Inonu University, Malatya 44280, Türkiye.
Diagnostics (Basel, Switzerland)
|March 14, 2026
概括
这项研究介绍了DE-SAMNet,这是一种用于从CT扫描中准确分类肺癌的深度学习模型. 可解释的AI框架提高了诊断可靠性,并支持早期检测.
科学领域:
- 医疗成像医学成像
- 人工智能的人工智能
- 在瘤学瘤学.
背景情况:
- 肺癌 (LC) 是全球癌症死亡的主要原因.
- 对于LC诊断的胸部CT扫描的手动解释是耗时且变化的.
- 需要自动诊断工具来提高准确性和效率.
研究的目的:
- 开发和评估DE-SAMNet,这是一个混合深度学习框架,用于自动化CT扫描的多类肺癌分类.
- 评估模型在公共和私人临床数据集上的表现.
- 使用可解释AI (XAI) 提高自动化分类的可解释性.
主要方法:
- DE-SAMNet集成了DenseNet121和EfficientNetB0以进行多级特征提取.
- 空间注意模块 (SAM) 通过专注于临床相关区域来完善特征表示.
- 一个紧的聚变机制结合了最终分类的特征.
主要成果:
- 该模型在公共数据集 (99.54%准确度) 和私人数据集 (95.96%准确度) 上实现了高性能.
- 在肺癌分类方面,DE-SAMNet的表现优于现有的方法.
- XAI技术 (Grad-CAM) 可视化了决策,突出了损伤特定区域的透明度.
结论:
- DE-SAMNet为自动肺癌检测提供了一个高度准确和可解释的解决方案.
- 可解释性特征增强了信任,并证明了早期诊断的临床潜力.
- 该框架解决了手动CT扫描解释方面的挑战,提高了诊断的一致性.
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