对于初级牙的可吸收根管填充材料的修改:系统性审查
Anna Błaszczyk-Pośpiech1, Sylwia Kiryk2, Natalia Nawrot3
1Pre-Clinical Research Center, Wrocław Medical University, Karola Marcinkowskiego 1, 50-368 Wrocław, Poland.
Materials (Basel, Switzerland)
|March 14, 2026
概括
对于母牙的可再吸收根管填充材料的修改显示出有希望的微生物抗菌活性在体外. 然而,有限的临床数据需要进一步的研究来证实它们的优越性.
科学领域:
- 牙科 牙科是指牙科的专业.
- 生物材料科学 生物材料科学
- 微生物学 微生物学
背景情况:
- 初始牙需要专门的根管填充材料.
- 评估物质修改对于改善治疗结果至关重要.
- 了解抗微生物性能是预防二次感染的关键.
研究的目的:
- 系统地审查基于材料的修改,用于母牙的可再吸收根管填充材料.
- 评估组合变化对抗菌素性能的影响.
- 评估生物活性添加剂,抗微生物剂和替代基质的影响.
主要方法:
- 在PubMed,Scopus,Web of Science和Embase的系统文献搜索.
- 搜索词集中在母牙,根管填充材料和抗菌剂上.
- 研究选择遵循PRISMA 2020标准和PICO框架,包括18项研究.
主要成果:
- 最常被研究的是基于氧化的改性材料.
- 添加,Morinda citrifolia,和橄油等添加剂改善了结果.
- 特里克洛桑显示出强烈的抗菌作用,而赫西丁的结果是可变的. 富含抗生素的材料是有效的,但引起了耐药性的担忧.
结论:
- 大多数修改在体外增强了抗微生物活性和物理化学特性.
- 临床证据有限且异质,阻止对优越性的最终结论.
- 需要进一步的长期随机临床试验来验证实验室发现.
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