相关实验视频

Updated: Mar 15, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

18.8K

尼特洛克通过抑制STAT3-AKT-MTOR生存信号来提高非小细胞肺癌的放射敏感性

Eun-Young Gong1, Hye Won Lee1, Hyunseung Oh2

  • 1Department of Pathology, Keimyung University School of Medicine, Daegu 1095, Republic of Korea.

International journal of molecular sciences
|March 14, 2026
PubMed
概括

抗微生物药物尼特素通过抑制STAT3信号来增强非小细胞肺癌 (NSCLC) 的辐射敏感性. 这种组合疗法促进癌细胞死亡和DNA损伤,提高了放射治疗的有效性.

关键词:
在 AKT AKT 里面.在STAT3中,我们可以使用STAT3.在mTOROR中使用mTOR.这是一种氧化 (nitroxoline) 化合物.非小细胞肺癌的肺癌.辐射敏感性 辐射敏感性无线电感应器 (Radiosensitizer) 是一种具有无线电感应力的装置.

更多相关视频

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo08:19

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on: July 20, 2019

6.5K
Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis11:44

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

Published on: March 30, 2019

8.1K

相关概念视频

mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
5.0K
PI3K/mTOR/AKT Signaling Pathway01:22

PI3K/mTOR/AKT Signaling Pathway

The mammalian target of rapamycin  (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1  (mTORC1) and mTOR complex 2  (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast,  mTORC2 consists of a...
6.1K