在Valeriana officinalis的金属含量L.根在西班牙地区 (特内里夫,加拿大群岛) 商业化
Juan R Jáudenes-Marrero1,2, Ángel Gutiérrez-Fernández1,2, Chaxiraxi Morales-Marrero3
1Toxicology Area, Universidad de La Laguna, La Laguna, 38071 Santa Cruz de Tenerife, Spain.
Foods (Basel, Switzerland)
|March 14, 2026
概括
用于治疗失眠和焦虑的草根补充剂被测试了金属含量. 虽然一些产品超过了限值,但治疗剂量的总体消费并不构成毒理风险.
科学领域:
- 药理学是指药理学,即药理学是指药理学.
- 环境化学环境化学
- 毒理学 毒理学 毒理学
背景情况:
- 瓦莱里亚纳 (Valeriana officinalis L.) 根是一种在加拿大群岛广泛使用的补充剂,用于治疗失眠和焦虑.
- 香对金属积累的敏感性需要进行风险评估,特别是在多剂量疗法中.
- 草药产品中金属的监管限制对于消费者安全至关重要.
研究的目的:
- 在根补充剂中量化金属度 (Cd, Pb, Al, Cr, Cu, Li, Ni, Sr, Mo, Zn, Co, Fe, B, Mn, V, Ba, K, Na, Mg, Ca).
- 评估与这些补充剂的消费相关的潜在毒理风险.
- 将金属含量与欧洲药典标准进行比较.
主要方法:
- 诱导合等离子光辐射光谱法 (ICP-OES) 用于金属分析.
- 分析了23个根样本 (碎片化,粉碎,粉碎).
- 确定金属度,并与已确定的安全限值进行比较.
主要成果:
- 六个样本超过了欧洲药典的 (Cd) 限值0.1 mg/kg.
- 超额样本包括Pinisan,EnRelax® (药丸和输注剂),Kneipp,Milvus以及一个市场样本.
- 尽管某些产品超过了Cd限值,但对金属的估计每日摄入量 (EDI) 没有表明有毒性风险.
结论:
- 某些根补充剂可能含有高水平的.
- 鉴于估计的每日摄入量,草根的治疗用途不太可能带来显著的毒理风险.
- 建议继续监测草药补充剂中的金属含量.
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