肥胖个体的饮食质量,肠道透性和肠道微生物群特征之间的关系
Sarah M Eaton1, Weiwen Chai1, Olivia Moss2
1Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Nutrients
|March 14, 2026
概括
这项研究发现,坚持健康的饮食模式,如HEI-2010,MDP和DASH,与肥胖个体的肠道透率降低有关. 改善饮食质量可能会促进更好的肠道健康.
科学领域:
- 营养科学 营养科学
- 微生物组研究 微生物组研究
- 胃肠病学 胃肠病学
背景情况:
- 肥胖与肠道微生物群的改变和肠道透性的增加有关.
- 饮食模式显著影响肠道健康和代谢结果.
- 了解饮食,肠道屏障功能和微生物群之间的相互作用对于管理与肥胖有关的健康问题至关重要.
研究的目的:
- 调查遵守三个饮食模式 (HEI-2010,MDP,DASH) 与肠道透性之间的关联.
- 探索这些饮食模式,肠道透性和肠道微生物群组成之间的关系.
- 检查饮食质量对肥胖人口肠道健康标志物的影响.
主要方法:
- 对103名健康的肥胖成年人进行了专项后期的横截面研究.
- 使用Vioscreen食物频率调查问卷评估的饮食摄入量.
- 通过尿路糖分泌测量肠道透性;微生物群以16S rRNA基因测序为特征.
主要成果:
- 更高的HEI-2010,MDP和DASH饮食模式的坚持与下肠透性相关.
- 在所有饮食模式中,水果摄入量始终与肠道透率降低有关.
- 较高的DASH分数与蛋白质细菌减少和维鲁科米克罗比亚丰度增加有关.
结论:
- 根据HEI-2010,MDP和DASH模式评估的饮食质量可能在维持肠道屏障完整性方面发挥作用.
- 某些特定的饮食成分,如水果,似乎对肠道健康有益.
- 研究结果表明,饮食干预可能是改善肥胖个体肠道健康的策略.
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