相关实验视频

Updated: Mar 15, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

Published on: August 30, 2016

人体肠道中益生菌驱动的竞争性排斥:微生物多样性和病原体抑制的元分析

Sumaya Sameer Alshatari¹, Malgorzata Ziarno²

¹Independent Researcher, 00-132 Warsaw, Poland.

|March 14, 2026

概括

益生菌,有益的活微生物,通过竞争性排斥有效抑制肠道病原体. 像Lacticaseibacillus和Bifidobacterium这样的特定菌株在防止病原体殖民方面表现出显著的有效性.

科学领域:

微生物学微生物学
胃肠病学胃肠病学
免疫学免疫学免疫学

背景情况:

肠道微生物群在宿主健康和疾病预防方面发挥着至关重要的作用.
益生菌被定义为活生生的有益微生物,因其抑制病原体的能力而得到认可.
竞争性排斥是益生菌发挥有益作用的关键机制.

研究的目的:

系统地评估益生菌在减少人类肠道中病原体殖民化的有效性.
为了分析研究益生菌媒介竞争性排斥的体内研究.
提供有关益生菌对病原体排除的影响的定量数据.

主要方法:

在PubMed和Scopus的综合文献搜索 (2018年10月 - 2023年8月).
包括报告益生菌竞争性排除的体内研究.
从符合条件的研究中获得的定量数据的元分析.

主要成果:

通过益生菌排除病原体的统计学上显著的聚合几率比为1.68 [1.13-2.51] (p < 0.01).
最小的异质性 (I2 = 0%) 表明了可靠的发现.
确定了包括Lacticaseibacillus,Limosilactobacillus和Bifidobacterium在内的特定属,作为有效的.

结论:

益生菌菌株,特别是乳菌,菌和双菌,在竞争性排斥方面是有效的.
研究结果支持使用益生菌来治疗胃肠道感染.
需要对菌株特异性影响和最佳益生菌剂量进行进一步的研究.

关键词:

这种细菌是Bifidobacterium.乳制品公司ibacillus.利莫西拉克托巴西勒斯 (Limosilactobacillus) 是一种植物.竞争中的排斥竞争中的排斥我们的肠道微生物群.肠道健康肠道健康这是一个元分析.微生物多样性的微生物多样性病原体抑制抑制病原体抑制益生菌是一种益生菌.

更多相关视频

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

相关概念视频

Bacterial Flora of the Large Intestine

Bacterial Flora of the Large Intestine

The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.

What is Monogastric Digestion?

What is Monogastric Digestion?

The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.