长期的甜菜提取物补充改善了绝经后妇女的形态肌肉质量和力量发展率:一项随机临床试验
Olavo João Frederico Ramos Junior1,2, Carlos Alberto de Souza Filho1,2, Shaheen Majeed3
1Nutrition and Exercise Metabolism Research Group, Multidisciplinary Center UFRJ-Macaé, Federal University of Rio de Janeiro, Macaé 21941-901, Rio de Janeiro, Brazil.
Nutrients
|March 14, 2026
概括
长期补充甜菜提取物改善了绝经后妇女的肌肉质量和力量发展. 这种食酸盐干预可以帮助预防与年龄相关的骨肌功能下降.
科学领域:
- 运动生理学 运动生理学
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 更年期相关的低雌激素降低了氧化 (NO) 的产生,损害了骨肌肉的质量和功能.
- 饮食中酸盐补充剂对绝经后肌肉健康的长期影响仍未确立.
- 这项研究解决了在这个人口群体中持续酸盐摄入量对肌肉质量的证据需求.
研究的目的:
- 评估酸盐丰富的甜菜提取物的12周影响肌肉质量,力量发展速度 (RFD),最大强度和绝经后妇女的酸盐/酸盐水平.
- 调查食酸盐补充剂在缓解更年期肌肉衰减方面的有效性.
- 确定甜菜补充剂对神经肌肉功能的长期益处.
主要方法:
- 一个为期12周的随机,双盲,安慰剂对照试验,涉及20名绝经后妇女.
- 参与者每天食用富含酸盐的甜菜提取物 (BET) 或酸盐贫乏的安慰剂 (PLA).
- 肌肉质量 (形态和功能),RFD,最大自愿同度收缩 (MVIC) 和血清酸盐/酸盐在基线,8周和12周被测量.
主要成果:
- 与PLA相比,BET在整个研究中显著提高了血清酸盐和酸盐的水平.
- 形态肌肉质量在BET组显著改善 (p=0.014).
- 早期阶段和峰值RFD与BET显著增加,增长持续了12周 (p<0.05). 在12周的BET组中,MVIC也增加了.
结论:
- 十二周的富含酸盐的甜菜提取物补充剂提高了绝经后妇女的形态肌肉质量和力量发展速度.
- 这些发现表明,甜菜补充剂在抵消与年龄相关的骨肌肉结构和神经肌肉衰退方面具有潜在的临床作用.
- 饮食中酸盐干预表明有望改善更年期肌肉功能.
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